Consumption of ultra-processed foods and cancer risk: results from NutriNet-Santé prospective cohort

Recent research conducted by a group of French Researchers concluded that consuming ultra-processed foods can increase the risk of developing cancer. This was published in : BMJ 2018; 360 doi: https://doi.org/10.1136/bmj.k322 (Published 14 February 2018)Cite this as: BMJ 2018;360:k322

Objective To assess the prospective associations between consumption of ultra-processed food and risk of cancer.

Design Population based cohort study.

Setting and participants 104 980 participants aged at least 18 years (median age 42.8 years) from the French NutriNet-Santé cohort (2009-17). Dietary intakes were collected using repeated 24 hour dietary records, designed to register participants’ usual consumption for 3300 different food items. These were categorised according to their degree of processing by the NOVA classification.

Main outcome measures Associations between ultra-processed food intake and risk of overall, breast, prostate, and colorectal cancer assessed by multivariable Cox proportional hazard models adjusted for known risk factors.

Results Ultra-processed food intake was associated with higher overall cancer risk (n=2228 cases; hazard ratio for a 10% increment in the proportion of ultra-processed food in the diet 1.12 (95% confidence interval 1.06 to 1.18); P for trend<0.001) and breast cancer risk (n=739 cases; hazard ratio 1.11 (1.02 to 1.22); P for trend=0.02). These results remained statistically significant after adjustment for several markers of the nutritional quality of the diet (lipid, sodium, and carbohydrate intakes and/or a Western pattern derived by principal component analysis).

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